Abstract #4197
Latency time variability hinders ASL fMRI analyses
Joao M. S. Pereira 1 , Joo Duarte 2 , Miguel Raimundo 3 , and Miguel Castelo-Branco 4
1
Laboratory of Biostatistics, IBILI - Faculty
of Medicine, University of Coimbra, Coimbra, Portugal,
2
ICNAS
- Faculty of Medicine, University of Coimbra, Coimbra,
Portugal,
3
Clinical
School - Faculty of Medicine, University of Coimbra,
Coimbra, Portugal,
4
Visual
Sciences Laboratory, IBILI - Faculty of Medicine,
University of Coimbra, Coimbra, Portugal
For functional imaging purposes, Arterial Spin Labeling
(ASL) has the advantage of measuring activity directly
related to neuronal activation with greater localizing
sensitivity than the more common BOLD signal analyses.
The application of ASL in the fMRI context has, however,
been blighted by subpar performances. This work
addresses the variability of the latency in the
hemodynamic response function (HRF) in both healthy
controls and diabetes type II patients, known to have
changes in brain vasculature. A method is presented to
bypass this limitation in ASL fMRI.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
