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Abstract #4330

Dynamic k T -points: a new concept to improve T 2 -weighted imaging at 7T

Florent Eggenschwiler 1 , Kieran R. O'Brien 2,3 , Bndicte Marchal 3,4 , Rolf Gruetter 1,2 , and Jos P. Marques 5

1 Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland, 2 Department of Radiology, University of Geneva, Geneva, Geneva, Switzerland, 3 CIBM - AIT, cole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland, 4 Advanced Clinical Imaging Technology, Siemens H IM BM PI, Lausanne, Vaud, Switzerland, 5 Department of Radiology, University of Lausanne, Lausanne, Vaud, Switzerland

At high field, the B 1 + inhomogeneity causes undesirable signal and contrast variations across the brain. It has been shown that those artifacts can be corrected by designing a single k T -point pulse in the STA regime to replace all the hard pulses of a TSE sequence. In this work, to further improve T 2 -weighted imaging, a specific k T -point pulse is designed for each sequence pulse (dynamic k T -point design). K T -points were thus included to the SR-EPG formalism in order to optimize the magnetization state throughout the TSE sequence such that the signal across the brain matches the targeted one for each sequence echo.

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