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Abstract #4331

Tailored RF pulse design method for CPMG sequences

Shaihan J Malik 1 and Joseph V Hajnal 1,2

1 Division of Imaging Sciences and Biomedical Engineering, Kings College London, London, London, United Kingdom, 2 Centre for the Developing Brain, Kings College London, London, United Kingdom

In fast spin echo (FSE) sequences pathways that meet the CPMG condition (90 phase between excited magnetization and refocusing pulses) are sustained, whereas non-CPMG pathways die away. We explore the suppression of non-CPMG pathways as an additional design flexibility for localized excitation pulses for inner-volume 3D-FSE imaging. The RF design problem is reformulated by splitting real and imaginary components and then a weighted optimization is used to unevenly distribute error to the non-CPMG channel. The approach is tested by designing multi-dimensional localized excitation pulses for a 3D-FSE imaging sequence and is shown to reduce excitation error and preserve background suppression.

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