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Abstract #4454

What do we gain from multiple q-shell acquistions in high angular resolution diffusion imaging?

Jonas Cordes 1 , Peter Neher 1 , Hans-Peter Meinzer 1 , Bram Stieltjes 2 , and Klaus Maier-Hein 1,2

1 Medical and Biological Informatics, German Cancer Research Center (DKFZ), Heidelberg, Baden-Wrttemberg, Germany, 2 Quantitative Image-based Disease Characterization, German Cancer Research Center (DKFZ), Heidelberg, Baden-Wrttemberg, Germany

Here we present a set of metrics and experiments that evaluate the performance of several single- and multi-shell high angular resolution diffusion imaging (HARDI) acquisition schemes. In particular, we assess the angular resolution, the peak accuracy, the peak precision as well as the distribution function accuracy and distribution function precision at several different fiber configurations. We show that low b-value acquisitions in a multi-shell configuration can reach similar performances as high b-value acquisitions on a single shell.

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