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Abstract #4456

Diffusion tensor imaging with 1mm isotropic resolution using a dual-echo steady-state method at 3T

Vincent Gras 1 , Ezequiel Farrher 1 , Farida Grinberg 1 , and N Jon Shah 1,2

1 INM-4, Research Centre Jlich GmbH, Jlich, Germany, 2 Department of Neurology, RWTH Aachen University, Aachen, Germany

We investigate the applicability of the dual echo steady state pulse sequence with diffusion-weighting field gradients (DW-DESS) to characterize the anisotropic diffusion of water molecules in a dedicated anisotropic diffusion fibre phantom. The conventional diffusion tensor imaging (DTI) model is used for the data analysis and a comparison with the gold standard pulse sequence for DTI, namely the DW spin-echo EPI sequence, is carried out. A good agreement between both pulse sequences is demonstrated. Finally the feasibility of applying DW-DESS for high resolution DTI in vivo is discussed.

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