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Abstract #4539

IVIM-DTI of Healthy Human Liver

Oi Lei Wong 1,2 and Michael D Noseworthy 3,4

1 Department of Medical Physics and Applied Radiation Science, McMaster University, Hamilton, Ontario, Canada, 2 Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong, Hong Kong, 3 Department of Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada, 4 Imaging Research Center, St.Joseph's Healthcare, Hamilton, Ontario, Canada

Both IVIM and DTI are well recognized MRI methods for quantifying flow and diffusion, respectively. Simultaneously assessing both techniques (IVIM-DTI) has recently been shown feasible in the kidney. We proposed that the same technique is also feasible in the liver with multiple breath holds and subsequent retrospective motion compensation. Based on our result, IVIM-DTI analysis is able to differentiate between hepatic blood vessels and liver parenchyma, while minimizing the pseudo-hepatic artifact.

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