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Abstract #4546

Changes in the Medial and Lateral Gastrocnemius Fiber Architecture with Age.

Yanjie Xue 1 , Usha Sinha 1 , Vadim Malis 1 , Robert Csapo 2 , and Shantanu Sinha 2

1 Physics, SDSU, San Diego, CA, United States, 2 Radiology, UCSD, San Diego, CA, United States

Age related changes in muscle alter fiber architecture (fiber lengths and pennation angles). Diffusion tensor imaging (DTI) allows the mapping of fiber architecture, this study investigates age related changes in fiber architecture of the medial and lateral gastrocnemius using DTI. Ten female subjects (5 young/ 5 old) were imaged using DTI and fiber length and pennation angles were determined. Decreases in fiber length and pennation angle were seen in the older cohort as well as regional differences between distal and middle origin fibers. The length/pennation angle changes in the LG were smaller than those seen in the MG.

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