Abstract #4587
Differences in K trans and v e parameters of gluteal and deep pelvic muscles
Milica Medved 1 , Aytekin Oto 1 , Xiaobing Fan 1 , Federico D Pineda 1 , Russell Z Szmulewitz 2 , and Gregory S Karczmar 1
1
Radiology, University of Chicago, Chicago,
Illinois, United States,
2
Medicine,
University of Chicago, Chicago, Illinois, United States
The determination of the arterial input function (AIF)
is critical to applications of the two compartment model
to tissue contrast agent uptake and washout. As the AIF
cannot always be measured directly, approximate methods
are sometimes used to derive it, such as using muscle
with known K
trans
and
v
e
values as a reference tissue. Published
values for skeletal muscle, such as the calf, are often
used, but we show significant differences in K
trans
and
v
e
between gluteal and deep pelvic muscles. We
conclude that skeletal muscles should be characterized
individually.
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