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Abstract #4603

Quantification of cerebral perfusion using dynamic quantitative susceptibility mapping

Bo Xu 1,2 , Pascal Spincemaille 2 , Tian Xu 3 , Martin Prince 2 , Silvina Dutruel 2 , Ajay Gupta 2 , Nandadeepa Thimmappa 2 , and Yi Wang 1,2

1 Cornell University, New York, NY, United States, 2 Weill Cornell Medical College, NY, United States, 3 MedImageMetric LLC, NY, United States

Quantitative susceptibility mapping (QSM) has the potential to quantify contrast agent bio-distribution. The purpose of this study is to develop a QSM technique with sufficient temporal resolution for mapping first pass contrast agent concentration in cerebral perfusion imaging.Initial in-vivo brain imaging data demonstrated the feasibility of mapping time resolved contrast agent quantification using the proposed method. Cerebral blood flow agrees with that obtained from arterial spin labeling technique.

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