Abstract #4622
Alterations in Cardiac-Correlated Brain BOLD Signal in Children with Chronic Kidney Disease
Hua-Shan Liu 1 , Abbas F. Jawad 2 , Nina Laney 2 , Stephen Hooper 3 , Jerilynn Radcliffe 2 , Divya Moodalbail 2 , Christos Davatzikos 1 , Robert Schultz 2 , Susan Furth 2 , and John Detre 1
1
University of Pennsylvania, Philadelphia,
PA, United States,
2
The
Childrens Hospital of Philadelphia, Philadelphia, PA,
United States,
3
University
of North Carolina School of Medicine, Chapel Hill, NC,
United States
We investigated the group difference of the
cardiovascular fluctuation-induced modulation in BOLD
fMRI signal between patients with chronic kidney disease
(CKD) and control subjects. We found that CKD patients
showed a significantly increased cardiac modulation in
BOLD fMRI in the anterior cingulated cortex as compared
with control subjects.
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