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Abstract #4650

Accurate PET Reconstruction for PET/MR Scanners using Synthetic CT

Snehashis Roy 1 , Wen-Tung Wang 1 , John Anthony Butman 2 , and Dzung Pham 1

1 Center for Neuroscience and Regenerative Medicine, Henry Jackson Foundation, Bethesda, MD, United States, 2 Diagnostic Radiology, National Institute of Health, Bethesda, MD, United States

In functional imaging, PET/CT images are regularly acquired in clinical setting. CT-based electron density attenuation coefficient maps enable correct reconstruction of PET images. Recently, the use of Magnetic Resonance Imaging (MRI) has been popularized in PET/MR systems. We demonstrate that Ultra-short echo time (UTE) dual-echo images can effectively be used to synthesize realistic looking CT via patch matching from subject to atlas. We show that PET reconstruction using synthetic CT based μ-maps are very close to that obtained with original CT based μ-maps and synthetic CT provides better PET reconstruction than DIXON based μ-map.

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