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Abstract #4649

Neonatal Asymmetry between Preterm and Term Neonates:An MRI Structural Network Study

Jing Wang 1,2 , Mengye Lyu 1,2 , Jie Gao 1 , Yumiao Zhang 1 , Yanyah Li 1 , Qinli Sun 1 , and Jian Yang 1,2

1 Department of Diagnostic Radiology, The First Hospital of Medical School, Xian Jiaotong University, Xi'an, Shaanxi, China, 2 Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China

Recent studied have demonstrated that neonatal brain networks have hemispheric asymmetry. However, changes of the asymmetry are not yet understood between preterm and term neonates. Our study compared network parameters of cerebral hemispheres between preterm and term neonates. The results showed more evident leftward asymmetry on term neonates with more efficient information transfer than preterm neonates. Moreover, comparing lateralization index of betweenness centrality in the cerebral hemispheres of preterm and term neonates, we concluded for term neonatal brain, left hemisphere has preferably evolved into regions with visual and language function while lateralized regions with cognitive functions come out in the right hemisphere.

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