Abstract #4648
Gender-Specific Templates of T1, T2 and mcDESPOT Myelin Water Fraction Map Spanning Early Childhood
Sean Deoni 1 , Jonathan O'Muircheartaigh 2 , Holly Dirks 1 , Nicole Waskiewicz 1 , Lindsay Walker 1 , and Douglas Dean 1
1
Advanced Baby Imaging Lab, Brown University,
Providence, Rhode Island, United States,
2
Neuroimaging,
King's College London, England, United Kingdom
Few studies to-date have aimed to comprehensively
investigate or map early infant brain development,
despite this period being a crucial period of brain and
behavioral maturation. In this work, we used the
mcDESPOT relaxometry method to quantitative evaluate T1,
T2 and myelin water fraction, VFM, in a large sample of
healthy and typically-developing children 2.5 months to
5.5 years of age. From 424 total datasets, 14 mean male
and female T1, T2 and VFM maps were created spanning 3
to 60 months of age. These publicly-available data (www.babyimaginglab.com/research.htm)
provide an unprecedented view into normal brain
development.
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