Abstract #4662
Frequency specificity of regional homogeneity in the resting-state human brain
Xiaopeng Song 1 , Yi Zhang 2 , Zhenyu Zhou 3 , and Yijun Liu 1
1
Department of Biomedical Engineering, Peking
University, Beijing, Beijing, China,
2
School
of Life Science and Technology, Xidian University,
Xi'an, Shanxi, China,
3
GE
Health care, Beijing, Beijing, China
To examine the frequency characteristics of regional
homogeneity (ReHo) in different brain areas, a
data-driven method, Empirical Mode Decomposition, was
adopted to decompose the time series of each voxel into
several components with distinct frequency bands. ReHo
in each of the components were then calculated. Results
showed that ReHo in cortical areas were higher and more
frequency-dependent than those in the subcortical
regions. BOLD oscillations of 0.02-0.04Hz mainly
contributed to the cortical ReHo, whereas the ReHo in
subcortical areas involved a wider frequency range. Our
work may advance the understanding of the
neural-physiological basis of local BOLD activities.
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