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Abstract #4704

Multiband Acquisitions for Clinically-Feasible 3-T MRI Track Density Imaging to Parcellate Thalamic Nuclei for Functional Neurosurgery

Timothy Shepherd 1 , Sohae Chung 1 , Christopher Glielmi 2 , Alon Mogilner 3 , Himanshu Bhat 4 , Stephen F Cauley 5 , Kawin Setsompop 5 , Fernando Boada 1 , and Douglas Kondziolka 3

1 Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 2 Siemens Healthcare, New York, NY, United States, 3 Department of Neurosurgery, New York University School of Medicine, New York, NY, United States, 4 Siemens Healthcare, Charlestown, MA, United States, 5 A.A. Martinos Center for Biomedical Imaging, Dept. of Radiology, MGH, Charlestown, MA, United States

This study combined two recent innovations, track density imaging (TDI) and multi-band diffusion acquisitions, to create a clinically feasible 3-T MRI protocol for thalamic parcellation to identify the ventral intermediate nucleus (VIM) in elderly patients with essential tremor prior to functional neurosurgery. This represents a rapid translation of novel research technology to clinical practice without requiring high-field MRI or long scan times poorly tolerated by real patients.

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