Characterization of a 60-minute MCAO using immunohistochemical evaluation in conjunction with MRI

This study examined the expression of an early and late marker of the apoptotic cascade associated with perfusion and diffusion abnormality at 2 and 24 hours following a 60 minute MCAO in rats. Quantitative correlations of apoptotic expression were made with ADC and CBF measures. We found a strong correlation of ADC and CBF values with molecular markers of apoptosis and cell death. The finding provide molecular underpinnings of quantitative prediction of ischemic fate and functional reorganization based on acute MRI data.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.