Abstract #4775
Data-driven analysis of Cerebrovascular reactivity reveals regional vascular impairment in individuals with multiple systemic risk factors
Ekaterina Tchistiakova 1,2 , David E. Crane 2 , Sandra E. Black 2,3 , and Bradley J. MacIntosh 1,2
1
Medical Biophysics, University of Toronto,
Toronto, ON, Canada,
2
Heart
and Stroke Foundation Canadian Partnership for Stroke
Recovery, Sunnybrook Research Institute, Toronto, ON,
Canada,
3
Department
of Medicine, Division of Neurology, University of
Toronto, Toronto, ON, Canada
Cerebrovascular impairment is a common complication in
individuals with cerebral small vessel disease (SVD).
The presence of systemic conditions such as diabetes and
hypertension can further hinder the maintenance of
cerebral blood flow, thereby increasing the risk of TIA
and stroke. In this study we examined the effects of
systemic risk factors on cerebrovascular function,
assessed using vascular reactivity metric (CVR), in
individuals with SVD in regions associated with specific
resting state networks. CVR decrease was associated with
increased number of risk factors within the
sensory-motor and default mode networks.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
