Abstract #4774
Differential Diagnosis of MELAS and Ischemic Stroke using 3D Pseudocontinuous Arterial Spin Labeling
Xin Lou 1 , Lin Ma 1 , Diandian Huang 1 , and Kaining Shi 2
1
Department of Radiology, Chinese PLA General
Hospital, Beijing, Beijing, China,
2
MR
Research (China), General Electric Company GE ( China )
Co., Ltd.-Healthcare, Beijing, Beijing, China
MELAS (mitochondrial myopathy, encephalopathy, lactic
acidosis, and a stroke-like episode) is a mitochondrial
disorder that the neurological deficits and imaging
characteristics resemble features of ischemic stroke.
Our study suggest that three dimensional
pseudo-continuous arterial spin labelling, an
alternative noninvasive perfusion technique based on
fast spin echo sequence, is useful in differentiating
MELAS from ischemic stroke when clinical symptoms and
conventional MRI manifestations overlap in these two
conditions.
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