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Abstract #4773

Global Effect of Focal Ischemic Stroke Revealed by Regional Homogeneity with BOLD fMRI

Lijuan Zhang 1 , Xiaojing Long 1 , Yanjun Diao 1 , Li Yi 2 , and Chunxiang Jiang 1

1 SIAT,Chinese Academy of Sciences, Shenzhen, Guangdong, China, 2 Neurology,Peking University Shenzhen Hospital, Guangdong, China

Global alteration of the functional synchronization was observed in brains with typical focal IS lesion in this study. The varied regional homogeneity may indicate a disintegrative dynamic of the functional homeostasis of human brain under the ischemic injury. Rebalance of the functional synchronization at a global level may provide valuable reference for disease management and rehabilitation of ischemic stroke.

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