Abstract #4792
3D high resolution MPRAGE helps identify intraplaque hemorrhage in patients with intracranial atherosclerotic diseases
Lei Zhang 1,2 , Qi Yang 3 , Xin Liu 1,2 , and Yiu Cho Chung 1,2
1
Paul C. Lauterbur Research Center for
Biomedical Imaging, Shenzhen Institutes of Advanced
Technology,Chinese Academy of Sciences, Shenzhen,
Guangzhou, China,
2
Shenzhen
Key Laboratory for MRI, Shenzhen Institutes of Advanced
Technology,Chinese Academy of Sciences, Shenzhen,
Guangzhou, China,
3
Radiology
Department, Xuanwu Hosptial, Capital Medical University,
Beijing, Beijing, China
Atherothrombotic intracranial disease is a major cause
of cerebral ischemia. Lesion enhancement may be detected
using high resolution T1 weighted imaging. MPRAGE are
commonly used to detect thrombus in carotid plaques and
other vascular beds. This study proposes the combined
use of T1 weighted imaging and MPRAGE to help identify
intraplaque hemorrhage. The protocol was applied in 10
patients diagnosed with intracranial artery stenosis. It
was found that the lesions may or may not enhance
post-contrast, and contrast enhancement of the lesion
may not have associated hyperenhancement in MPRAGE.
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