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Abstract #0045

Comparison of BOLD and CBV-weighted resting state connectivity to an anatomical gold standard in the motor network of the squirrel monkey brain

Yurui Gao 1,2 , Feng Wang 2,3 , Iwona Stepniewska 4 , Ann S Choe 1,2 , Kurt G Schilling 1,2 , Landman A Bennett 2,5 , Adam W Anderson 1,2 , Zhaohua Ding 2,3 , Limin Chen 2,3 , and John C Gore 2,3

1 Department of Biomedical Engeneering, Vanderbilt University, Nashville, Tennessee, United States, 2 Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee, United States, 3 Department of Radiology and Radiological Science, Vanderbilt University, Nashville, Tennessee, United States, 4 Department of Psychology, Vanderbilt University, Tennessee, United States, 5 Department of Electrical Engeneering, Vanderbilt University, Nashville, Tennessee, United States

This study aims to compare functional connectivity acquired using resting state MRI against the anatomical connectivity revealed by neurotracers injected into primary motor cortex (M1). BOLD timecourse correlation, CBV-weighted timecourse correlation and histological fiber strength were calculated, spacial normalized and compared. The comparison indicates the relationship between function and anatomy in motor network of squirrel monkey during resting state.

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