Abstract #0066
Application of 3D High-resolution Multi-echo TOF-SWI Acquisition in Radiation-induced Cerebral Microbleeds at 3T
Xiaowei Zou 1 , Wei Bian 2 , Jonathan I. Tamir 3 , Suchandrima Banerjee 4 , Susan M. Chang 5 , Michael Lustig 3 , Sarah J. Nelson 1 , and Janine M. Lupo 1
1
University of California San Francisco, San
Francisco, California, United States,
2
Radiology,
Stanford University, Stanford, California, United
States,
3
Electrical Engineering and Computer
Science, University of California Berkeley, Berkeley,
CA, United States,
4
Global
Applied Science Laboratory, GE Healthcare, Menlo Park,
CA, United States,
5
Neurological
Surgery, University of California San Francisco, San
Francisco, CA, United States
Radiation therapy is a widely utilized treatment for
gliomas. However, it can result in collateral injury to
normal-appearing brain tissue, such as the formation of
cerebral microbleeds (CMBs). The ability to assess
characteristics of CMBs in conjunction with the
surrounding arterioles and venules would help to
identify underlying vascular injury. In this study, a
seven-echo sequence was implemented and optimized for
multi-echo multi-contrast high-resolution vascular
imaging at 3T within a clinically feasible scan time.
The fitted R2* maps can differentiate small-size CMBs
and cystic changes, demonstrating the potential benefit
of this sequence in routine clinical evaluation of CMBs.
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