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Abstract #0115

Metal Artifact Reduction Using a 3D UTE-MSI sequence with Time-Frame Regularized Compressed Sensing Reconstruction

Yifei Lou 1 , Qun He 2 , Xun Jia 3 , Eric Chang 2 , Christine B Chung 2 , and Jiang Du 2

1 Department of Mathematical Sciences, University of Texas Dallas, Dallas, TX, United States, 2 Radiology, University of California, San Diego, CA, United States, 3 Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, United States

Metallic implants are routinely used to treat advanced joint disease. There is a need for non-invasive diagnosis of wear-induced disease. MRI has obvious advantages. However, conventional MR sequences are subject to severe distortion due to strong susceptibility effects near metal, with little or no signal from important joint tissues such as tendons and cortical bone which have very short T2s. 3D ultrashort echo time (UTE) imaging sequences together with multiple spectral imaging (MSI) can potentially image short T2 tissues and minimize metal artifact. However, 3D UTE-MSI is time-consuming. In this study we aimed to develop 3D UTE-MSI using with vastly undersampling to reduce scan time and a tight-frame regularized compressive sensing (TFCS) technique to reduce streak artifacts. T1, magnetization transfer ratio (MTR) and water content of tissues near metal can potentially being measured using a clinical whole-body scanner

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