Effects of bath solutions on the quantitative determination of relaxation times in compressed articular cartilage by microscopic MRI
Nian Wang 1 and Yang Xia 1
Department of Physics and Center for
Biomedical Research, Oakland University, Rochester, MI,
A new type of laminar appearance was found in the deep
region of compressed articular cartilage at the magic
angle by high-resolution MRI, but the origin of this
appearance was unclear. Recently, the molecular origin
of this loading-induced laminar layer in the deep
cartilage was attributed to the GAG loss in cartilage.
To investigate the characteristics of this additional
low-intensity layer, quantitative MRI T1, T2, and T1ρ
experiments were carried out under different
orientations when the tissue was soaked in different
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