Cartilage MR T1ρ and T2 quantifications: longitudinal reproducibility and variations using different coils and scanners at single and multi-sites
Xiaojuan Li 1 , Valentina Pedoia 1 , Deepak Kumar 1 , Drew Lansdown 1 , Cory Wyatt 1 , Julien Rivorie 1 , Narihiro Okazaki 1 , Dragana Savic 1 , Matthew F Koff 2 , Joel Felmlee 3 , Williams Steven 3 , and Sharmila Majumdar 1
University of California, San Francisco, CA,
for Special Surgery, New York, NY, United States,
Clinic, Rochester, MN, United States
MR T1ρ and T2 mapping are promising techniques that have
potential as early markers of cartilage degeneration.
Currently, applications of cartilage T1ρ and T2 imaging
in multicenter clinical trials are very limited. One
impeding factor is the lack of documentation of
potential variations of T1ρ and T2 introduced by
different scanners, coils and sites. In this report, we
evaluate the longitudinal reproducibility of T1ρ and T2,
and the variation of T1ρ and T2 by using different
scanners and coils at one site, and the reproducibility
and cross-validation of T1ρ and T2 among three sites.
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