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Abstract #0121

Regional brain T1 and T2 relaxometry in healthy volunteers using magnetic resonance fingerprinting

Chaitra Badve 1 , Alice Yu 2 , Matthew Rogers 2 , Dan Ma 2 , Jeffrey Sunshine 1 , Vikas Gulani 1 , and Mark Griswold 1

1 Radiology, University Hospitals Case Medical Center, Cleveland, Ohio, United States, 2 Case Western Reserve University, Ohio, United States

This is the first in vivo application of magnetic resonance fingerprinting in a large sample of normal subjects. MRF based relaxometry proves to be a fast and accurate tool to quantify microstructural patterns in brain based on aging, gender differences and differences between hemispheres. The study shows that aging related differences are seen more conspicuosly in certain brain regions over others. These findings not only serve to enhance understanding of physiological variations but also can serve as reference for evaluating various pathological states.

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