Leveraging transverse relaxation processes and Dixon oscillations to achieve high-quality segmentation of bone marrow
Mukund Balasubramanian 1,2 , Delma Y. Jarrett 1,2 , and Robert V. Mulkern 1,2
Department of Radiology, Boston Children's
Hospital, Boston, MA, United States,
Medical School, Boston, MA, United States
We demonstrate that gradient-echo sampling of single
spin-echoes can be used to isolate the signal from bone
marrow, with high-quality segmentation and surface
reconstruction resulting from the application of simple
post-processing strategies available on modern radiology
workstations. Our approach exploits signal behavior due
to reversible and irreversible transverse relaxation, in
concert with "Dixon oscillations", i.e., signal
oscillations due to chemical-shift interference effects.
The resulting 3D reconstructions could prove useful for
orthopedic surgical planning, providing an alternative
to computed tomography (CT) in situations where
eliminating exposure to ionizing radiation is a high
priority, e.g., when imaging pediatric patients.
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