Abstract #0137
Odor-evoked fMRI maps are coupled to calcium-sensitive dye imaging patterns of input activity in the olfactory bulb
Basavaraju G Sanganahalli 1 , Michelle R Rebello 2 , Peter Herman 1 , Gordon M Shepherd 3 , Justus V Verhagen 2,4 , and Fahmeed Hyder 1,5
1
Diagnostic Radiology, Yale University, New
Haven, CT, United States,
2
The
John B. Pierce Laboratory, Yale University, New Haven,
CT, United States,
3
Neurobiology, Yale
University, New Haven, CT, United States,
4
Neurobiology,
Yale University, CT, United States,
5
Biomedical
Engineering, Yale University, New Haven, CT, United
States
To improve functional understanding of odor-evoked
glomerular activity patterns revealed by BOLD signal and
to relate how input activities of glomeruli reflected by
calcium imaging relate to bulk neuropil activity of
fMRI, we designed a study to image the same rats with
fMRI first and then with calcium imaging. Excellent
correspondence between odor-evoked fMRI maps and
calcium-sensitive dye imaging patterns of input activity
suggests input activity is a dominant part of neuropilar
activity in glomeruli. In conclusion, multi-modal
functional imaging of rat olfactory bulb with odorant
stimulation provides new opportunities for gaining
insights into complexities of neuropilar activities.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
