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Abstract #0144

Accuracy of liver fat quantification by CT, MRI and US: a prospective comparison with Magnetic Resonance Spectroscopy (MRS)

Harald Kramer 1,2 , Mark A Kliewer 2 , Perry J Pickardt 2 , Diego Hernando 2 , Guang-Hong Chen 2 , and Scott B Reeder 2

1 Department of Clinical Radiology, University of Munich, Munich, Bavaria, Germany, 2 Department of Radiology, University of Wisconsin - Madison, Madison, Wisconsin, United States

Fatty infiltration of hepatocytes is the hallmark feature of non-alcoholic fatty liver disease (NAFLD) and potentially leads to inflammation, fibrosis and cirrhosis. Since the currently accepted diagnostic standard biopsy represents an invasive procedure and samples only very circumscribed regions within the liver, there is a need for a comprehensive, accurate and non-invasive quantitative biomarker.

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