Abstract #0158
A processing pipeline and anisotropic diffusion phantom to calibrate DTI experiments
Alexandru V. Avram 1 , Michal E. Komlosh 1,2 , Alan S. Barnett 1,2 , Elizabeth Hutchinson 1,2 , Dan Benjamini 1,3 , and Peter J. Basser 1
1
Section on Tissue Biophysics and
Biomimetics, NICHD, National Institutes of Health,
Bethesda, MD, United States,
2
The
Henry Jackson Foundation, Bethesda, MD, United States,
3
Department
of Biomedical Engineering, Tel-Aviv University,
Tel-Aviv, Israel
Experimental design and environmental factors can bias
the quantitation of anisotropic diffusion using
DTI-derived metrics, such as FA, compromising the value
of longitudinal data and multicenter clinical studies.
We propose the use of a novel anisotropic diffusion
phantom in conjunction with a general method for
modeling the diffusion signal produced by that phantom
using the details of the DWI pulse sequence and the
multiple correlation function (MCF) framework. The
well-defined and known microstructure of the phantom
generates a wide range of DTI parameters that can be
used to calibrate various DTI pulse sequences and
optimize clinical DTI protocols.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
