Abstract #0159
A novel phantom for quantitative diffusion MRI based on acetone and deuterium oxide
Xiaoke Wang 1 , Scott B. Reeder 2,3 , and Diego Hernando 2
1
Biomedical Engineering, University of
Wisconsin, Madison, Wisconsin, United States,
2
Radiology,
University of Wisconsin, Madison, Wisconsin, United
States,
3
Medical
Physics, University of Wisconsin, Madison, Wisconsin,
United States
Phantoms exhibiting desired diffusion behavior could
provide a controlled means for validation of
quantitative diffusion MRI techniques. Ideally, such
phantoms should possess a single-peak MR spectrum and
ADC values over the entire physiological range at a
controlled temperature. Recently proposed phantoms such
as PVP and sucrose phantoms may not meet all of these
requirements. The purpose of this study is to
investigate the spectral diffusion behavior of sucrose
and PVP phantoms, and propose acetone D2O mixture as an
alternative. Sucrose phantom showed multiple spectral
peaks. PVP phantom showed narrow ranged ADC. Acetone-D2O
phantom meets the requirements described above.
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