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Abstract #0177

Coronary Endothelial Function Assessment Using Self-Gated Cardiac Cine MRI with golden angle acquisition and k-t Sparse SENSE

Jerome Yerly 1,2 , Giulia Ginami 1,2 , Giovanna Nordio 1,2 , and Matthias Stuber 1,2

1 Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2 Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Coronary endothelial function (CEF) can be assessed non-invasively by measuring the vasodilatation of the coronary arteries in response to isometric handgrip exercise using bright blood cine MRI. However, cine MRI requires an external ECG signal to synchronize the data acquisition, which can be challenging to obtain in patients at high field strength. To address this hurdle, we propose a cardiac self-gated technique that combines golden angle radial acquisition with k-t sparse SENSE to reconstruct cardiac cine images without ECG. We demonstrate that our framework can accurately assess CEF and provide results equivalent to those of the standard ECG-gated technique.

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