A streamlined approach to mapping the oxygen extraction fraction (OEF) and deoxygenated blood volume (DBV) using the quantitative BOLD technique

There is a need for an easy-to-implement MR method capable of providing quantitative parametric maps of OEF and DBV across the brain in a clinically feasible timescale. In this study a FLAIR GESEPI ASE sequence is used to provide a refined measure of R ₂ ′ through optimisation of the data acquisition. The components of the sequence are selected to minimise confounds associated with CSF partial volume effects (FLAIR), macroscopic field inhomogeneities (GESEPI) and R ₂ -weighting (ASE) of the R ₂ ′ signal. This affords a simplified application of the qBOLD signal model, allowing parametric maps of OEF and DBV to be produced in a streamlined process.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.