Abstract #0223
Investigating the Impact of a Primary Tumor on Metastasis and Dormancy Using MRI: New Insights into the Mechanism of Concomitant Tumor Resistance
Paula Foster 1,2 , Amanda Hamilton 1 , and Carmen Simedrea 1
1
Imaging, Robarts Research Institute, London,
Ontario, Canada,
2
Medical
Biophysics, Western University, London, Ontario, Canada
MRI was used to track growth of brain metastases and
dormant (non proliferative) cancer cells in a mouse
model of concomitant tumor resistance. Our major result
was that the presence of a primary mammary fat pad tumor
limited the development of secondary metastases in the
brain.
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