Abstract #0251
Quantitative NMR imaging of the short-T2 components in the SKM tissue: alterations observed in myopathic patients
Ericky Caldas de A. Araujo 1 , Noura Azzabou 1 , Alexandre Vignaud 2 , Genevive Guillot 3 , and Pierre G. Carlier 1,4
1
NMR Laboratory, Institute of Myology, Paris,
le-de-France, France,
2
CEA/DSV/I2BM/NeuroSpin/UNIRS,
Gif Sur Yvette, le-de-France, France,
3
IR4M/UMR8081/CNRS,
University Paris-SUD, Orsay, le-de-France, France,
4
NMR
Laboratory, CEA/I2BM/MIRCen, Paris, le-de-France,
France
UTE methods offer the possibility of acquiring NMR
signal from protons in the hydration layers of the
collagen. We have applied the UTE method for imaging the
short-T2 signal in SKM tissue, which we hypothesise to
reveal intramuscular connective tissue content.
Dual-echo acquisition and selective long-T2 suppression
methods fail to isolate the short-T2 signals in SKM. We
propose a new method for processing UTE data, resulting
in signal issued exclusively from the short-T2
components in the SKM. The proposed method was applied
to investigate the SKM tissue of eight healthy
volunteers and three patients diagnosed with NMDs.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
