Correlation analysis between renal perfusion and estimated glomerular filtration rate in volunteers and patients with chronic kidney disease: an arterial spin labeling in 3.0T MRI study

The aim of this study is investigate the correlation between renal perfusion and estimated glomerular filtration rate (eGFR) in volunteers and patients with chronic kidney disease (CKD) by using the flow-sensitive alternating inversion recovery technique in 3.0T magnetic resonance imaging (MRI). The results demonstrated that the significant difference in perfusion among healthy volunteers, CKD group with eGFR 60ml/min/1.73m2, and CKD group with eGFR< 60ml/min/1.73m2. Moreover, the perfusion values in CKD patients increased with the increase of eGFR. It indicates that FAIR-ASL can reflect the renal blood flow perfusion, thus indirectly reflecting early renal function change.

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