Determination of Technically and Physiologically caused Variation of Parameters from DTI and BOLD MRI in Native Kidneys: A Repeatability Study

We evaluated the reproducibility of DTI and BOLD MRI parameters in native kidneys of healthy volunteers by performing three scans. Two scans were performed back-to-back with one hour break in between, followed by the third scan after three weeks. High reproducibility was obtained for ADC, FA, and R2* from DTI and BOLD measurements. The coefficients of variation between the scans separated by 3 weeks were similar to those for the back-to-back scans, indicating that the variances are primarily due to technically caused variances between scans rather than normal physiological variation over time.

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