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Abstract #0257

Determination of Technically and Physiologically caused Variation of Parameters from DTI and BOLD MRI in Native Kidneys: A Repeatability Study

Maryam Seif 1 , Chris Boesch 1 , and Peter Vermathen 1

1 Depts. Radiology and Clinical Research, University Bern, Bern, Switzerland

We evaluated the reproducibility of DTI and BOLD MRI parameters in native kidneys of healthy volunteers by performing three scans. Two scans were performed back-to-back with one hour break in between, followed by the third scan after three weeks. High reproducibility was obtained for ADC, FA, and R2* from DTI and BOLD measurements. The coefficients of variation between the scans separated by 3 weeks were similar to those for the back-to-back scans, indicating that the variances are primarily due to technically caused variances between scans rather than normal physiological variation over time.

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