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Abstract #0264

Time- and vessel encoded pCASL: a free lunch with all the trimmings

Thomas W Okell* 1 , Wouter Teeuwisse* 2,3 , Michael A Chappell 1,4 , and Matthias J.P. van Osch 2,3

1 FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, Oxfordshire, United Kingdom, 2 dept. of Radiology, C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands, 3 Leiden Institute for Brain and Cognition, Leiden, Netherlands, 4 IBME, Department of Engineering Sciences, University of Oxford, Oxford, United Kingdom

Combined with cerebral blood flow (CBF) and bolus arrival time maps, flow territory mapping delivers a profound insight into the patients hemodynamics. In this study, time encoded pCASL is extended with vessel encoding gradients to acquire CBF, bolus arrival time and flow territory maps with a single scan. Results are compared to those of dedicated CBF and flow territory pCASL scans, demonstrating that the post labeling delay in standard pCASL, which is normally idle time, can be utilized to generate both vascular territory and bolus arrival time maps without adversely affecting CBF quantification.

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