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Abstract #0271

Prospective motion correction for artefact reduction in pseudo-continuous arterial spin labelling with a 3D GRASE readout.

Benjamin Knowles 1 , Federico von Samson-Himmelstjerna 2,3 , Matthias Guenther 2,4 , and Maxim Zaitsev 1

1 Medical Physics, University Medical Centre, Freiburg, Germany, 2 Fraunhofer Mevis, Bremen, Germany, 3 Charit Medical University, Center for Stroke Research, Berlin, Germany, 4 University of Bremen, Germany

Arterial spin labelling (ASL) is a non-invasive method to measure blood perfusion. One limitation to ASL is that motion is highly corruptive, and leads to errors in perfusion-weighted images. This is especially problematic for 3D. In this study, the effectiveness of prospective motion correction (PMC) with an optical camera for artefact reduction in a pseudocontinuous ASL sequence with a 3D GRASE readout is investigated. Data are acquired using single-shot and segmented techniques. Segmented readouts are found to be strongly improved with PMC, even for compliant subjects. For single-shot, an intra-readout correction may still be required.

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