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Abstract #0276

Arterial Spin Labeling without control/label pairing and post-labeling delay: an MR fingerprinting implementation

Pan Su 1 , Deng Mao 1 , Peiying Liu 1 , Yang Li 1 , Babu G. Welch 2 , and Hanzhang Lu 1

1 Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, Dallas, Texas, United States, 2 Department of Neurological Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States

Conventional Arterial Spin Labeling (ASL) sequence is limited to the scheme of control/label pairing pulse and long post-labeling delay, which is an inefficient method to measure cerebral perfusion. Based on the all in one scan concept of the Magnetic Resonance Fingerprinting (MRF), we developed an ASL sequence that does not use post-labeling delay or control/label pairing to jointly measure cerebral blood flow (CBF), arterial transit time and T1. Preliminary scan result in healthy volunteers and in vascular disease patient showed promises of this novel technique.

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