Abstract #0282
Measurement of the Oxygen Extraction Fraction in Patients with Steno-occlusive Cerebrovascular Diseases using Quantitative Susceptibility Mapping at 7T
Ikuko Uwano 1 , Makoto Sasaki 1 , Kohsuke Kudo 2 , Ryota Sato 3 , Yuiko Sato 4 , Yasushi Ogasawara 4 , Hiroaki Saura 4 , Kuniaki Ogasawara 4 , Taisuke Harada 1 , Kenji Ito 1 , Fumio Yamashita 1 , Jonathan Goodwin 1 , and Satomi Higuchi 1
1
Division of Ultrahigh Field MRI, Institute
for Biomedical Sciences, Iwate Medical University,
Yahaba, Iwate, Japan,
2
Department
of Diagnostic and Interventional Radiology, Hokkaido
University Hospital, Sapporo, Hokkaido, Japan,
3
Central
Research Laboratory, Hitachi, Ltd., Kokubunji, Tokyo,
Japan,
4
Department of Neurosurgery, Iwate
Medical University, Morioka, Iwate, Japan
This study aims to determine the accuracy of oxygen
extraction fraction (OEF) maps generated from
quantitative susceptibility mapping (QSM) at 7T. We
compared relative OEF values of the affected cerebral
hemisphere against the contralateral hemisphere between
QSM and PET in patients with chronic unilateral internal
carotid artery or middle cerebral artery
stenosis/occlusion. Relative QSM-OEF values showed
excellent agreements with the corresponding PET-OEF
values. Therefore, OEF measurement using QSM at 7T is
considered comparable to that using PET and can be
applied for the assessment of patients with
steno-occlusive cerebrovascular diseases.
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