Abstract #0285
High Conspicuity Imaging and Initial Quantification of the Habenula on 3T QSM Images of Normal Human Brain
John Schenck 1 , Dominic Graziani 1 , Ek Tsoon Tan 1 , Seung-Kyun Lee 1 , Luca Marinelli 1 , Thomas Foo 1 , Christopher Hardy 1 , Tian Liu 2 , and Yi Wang 3
1
MRI Laboratory, General Electric Global
Research, Schenectady, New York, United States,
2
MedImageMetric,
New York, New York, United States,
3
Radiology,
Cornell Medical College, New York, New York, United
States
The habenular nuclei are two small (mm-sized) cell
masses deep in the brain near the midline on either side
of the 3rd ventricle. They are currently of intense
neuropsychological interest as they have been implicated
as having major roles in normal brain functioning and in
serious psychiatric disorders (e.g., depression).
However, they are not normally seen as conspicuous brain
components on conventional MRI images. We have
demonstrated that using QSM imaging on normal volunteers
using a conventional 3T scanner the habenulae can be
identified and quantified as conspicuous, paramagnetic
iron-rich structures.
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