Abstract #0288
Imaging Magnetic Susceptibility of the Human Knee Joint at 3 and 7 Tesla
Hongjiang Wei 1 , Bin Wang 1 , Xiaopeng Zong 2 , Weili Lin 2 , Nian Wang 1 , and Chunlei Liu 1,3
1
Brain Imaging and Analysis Center, Duke
University, Durham, NC, United States,
2
Biomedical
Research Imaging Center, University of North Carolina at
Chapel Hill, NC, United States,
3
Depatment
of Radoilogy, School of Medicine, Duke University, NC,
United States
The knee joint is one of the most important joints in
the human body with several intricate structures and
complex interfaces including bones, tendons, muscles,
fat, ligaments, cartilages and meniscuses. Each of these
components has unique molecular and cellular composition
and microstructures and thus may exhibit varying
magnetic susceptibility. Quantitative susceptibility
mapping (QSM) has been widely investigated in the brain,
e.g. for quantifying iron deposits and myelination.
However, these techniques have not been successfully
implemented in the knee. The purpose of this work was to
develop and demonstrate feasibility of water-fat
separated QSM in the knee as well as to evaluate the
susceptibility properties of different anatomical
structures within the knee joint. Imaging susceptibility
of the knee may aid in assessing knee joint diseases and
disorders.
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