Meeting Banner
Abstract #0314

Removing the confounding effect of the fat component in ADC quantification of the vertebral bone marrow water component

Michael Dieckmeyer 1 , Stefan Ruschke 1 , Holger Eggers 2 , Hendrik Kooijman 3 , Ernst J. Rummeny 1 , Jan S. Bauer 4 , Thomas Baum 1 , and Dimitrios C. Karampinos 1

1 Diagnostic and Interventional Radiology, Technische Universitt Mnchen, Munich, Germany, 2 Philips Research Laboratory, Hamburg, Germany, 3 Philips Healthcare, Hamburg, Germany, 4 Diagnostic and Interventional Neuroradiology, Technische Universitt Mnchen, Munich, Germany

The quantification of the apparent diffusion coefficient (ADC) of water in vertebral bone marrow has shown merit towards differentiating between benign and malignant vertebral compression fractures and towards indirectly investigating bone matrix changes in patients with osteoporosis. Vertebral bone marrow contains both water and fat components. Therefore, the extraction of water ADC can be biased by incomplete fat suppression of the secondary fat peaks close to the water peak, when using a spectrally selective fat suppression technique. The present work proposes a methodology to correct for the confounding effect of incomplete fat suppression in bone marrow water ADC quantification.

This abstract and the presentation materials are available to members only; a login is required.

Join Here