Abstract #0357
LAMINAR DIFFERENCES IN NEURAL ACTIVITY DURING POSITIVE AND NEGATIVE BOLD CONDITIONS
Daniel Zaldivar 1 , Nikos Logothetis 1 , and Jozien Goense 1,2
1
Logothetis, Max Planck Institute for
Biological Cybernetics, Tuebingen, Baden-Wrttemberg,
Germany,
2
Institute
of Neuroscience and Psychology, University of Glasgow,
Glasgow, United Kingdom
There is still debate whether negative BOLD responses
have a neural or vascular origin. Laminar differences in
neurovascular coupling have also been observed during
the negative-BOLD response. We investigated whether
these differences have a neural origin by performing
laminar recordings in V1. We positioned two laminar
electrodes in V1; one of these was located in the
negative-BOLD area whereas the other in the
positive-BOLD area. We observed that the middle cortical
layers did not decrease their neural activity while all
other layers did, suggesting that the negative BOLD
response is driven by the neural activity reductions in
the supragranular and infragranular layers.
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