Abstract #0384
Assessment of the Hepatocyte Fraction for estimation of liver function
TOMOYUKI OKUAKI 1 , Kosuke Morita 2 , Tomohiro Namimoto 3 , Morikatsu Yoshida 3 , Shinya Shiraishi 3 , Yasuyuki Yamashita 3 , and Marc Van Cauteren 1
1
Philips Healthcare, Minato-ku, Tokyo, Japan,
2
Department
of Central Radiology, Kumamoto University Hospital,
Kumamoto, Japan,
3
Department
of Diagnostic Radiology, Faculty of Life Sciences,
Kumamoto University, Kumamoto, Japan
The hepatocyte fraction(HeF) map is calculated from R1
maps acquired using a breathhold Look-Locker sequence
pre and post Gd-EOB-DTPA. Further, the kHep value is
calculated as uptake function. The resulting HeF and
kHep were compared to the results of 99mTc-GSA
scintigraphy. Seventy five patients were classified into
four severity levels based on scintigraphy. The median
values of the HeF of Normal, Mild, Moderate and Severe
were 76.7%, 72.5%, 50.4% and 44.8% respectively. The HeF
and kHep decreased with liver function deterioration.
The HeF is useful for a robust evaluation of liver
function and kHep provides information about hepatic
uptake.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
