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Abstract #0428

Adapting volumetric 1H echo-planar spectroscopic imaging of the human brain from 3 to 7 Tesla

Karim Snoussi 1,2 , Joseph S. Gillen 1,2 , Michael Schr 1,2 , Richard A.E. Edden 1,2 , Andrew A. Maudsley 3 , and Peter B. Barker 1,2

1 Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medidine, Baltimore, Maryland, United States, 2 Kennedy Krieger Institute, Johns Hopkins University, Baltimore, Maryland, United States, 3 Miller School of Medicine, University of Miami, Miami, Florida, United States

MR spectroscopy at high field is expected to benefit from improved signal-to-noise ratios and spectral resolution, due to increased chemical shift dispersion and reduced strong coupling effects. This study describes the development of a volumetric proton echo-planar spectroscopic imaging (EPSI) sequence for 7T. It is demonstrated in vivo that the spin-echo 7T EPSI sequence can be used to record high quality spectroscopic imaging data with extended 3D coverage and low RF power deposition.

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