Artifact-free T2* mapping without post hoc corrections

Macroscopic susceptibility differences are a frequent source of artifacts in T2* mapping, and post hoc correction methods are often cumbersome or inaccurate. We demonstrate that Fourier encoding is largely insensitive to macroscopic phase gradients up to a threshold determined by the Nyquist limit. Accurate T2* maps can thus be obtained without post hoc correction simply by acquiring data in 3D mode and truncating the echo train where the local phase gradient exceeds the threshold. This approach produces uniform T2* maps in phantoms despite the presence of a ferromagnetic object, and artifact-free T2* maps of the brain even near the sinuses.

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