Meeting Banner
Abstract #0443

Fast dynamic measurements of T 1 relaxation times: influence and correction of T 2 * effects

Olaf Dietrich 1 , Maximilian Freiermuth 1 , Linus Willerding 2 , Michael Peller 1 , and Maximilian F Reiser 1

1 Josef Lissner Laboratory for Biomedical Imaging, Institute for Clinical Radiology, LMU Ludwig Maximilian University of Munich, Munich, Germany, 2 Department of Internal Medicine III, LMU Ludwig Maximilian University of Munich, Munich, Germany

The purpose of this study was to analyze and correct the influence of contrast-agent induced T2* (transverse) relaxation effects on the accuracy of fast dynamic 3D gradient-echo T1 measurements with a combined variable-flip-angle baseline measurement and subsequent single-flip-angle measurements during the dynamic phase. Previously proposed techniques for T1 quantitation neglect the influence of transverse relaxation effects on the measured signal during the dynamic phase and result in systematically increased T1 values. We demonstrate that the influence of transverse relaxation can be expressed as a function of T1 leading to an implicit expression for T1 that can be solved numerically.

This abstract and the presentation materials are available to members only; a login is required.

Join Here