Full 3D Renal BOLD MRI in Clinically Realistic Scan Times with 2D Volume Selective Excitation

BOLD MRI has the potential to depict renal hypoxia, but published data are contradictory, likely secondary to limitations in the underlying MRI technique. We have successfully applied 2-dimensional volume selective excitation to reduce the scan time required for full 3D high-resolution renal BOLD imaging of a single kidney to just over 1.5 minutes. This clinically realistic scan time opens the door for the wider investigation of renal BOLD MRI and its ultimate application to assessment of chronic kidney disease progression and response to therapy.

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